教育經(jīng)歷
2003-09至2009-07,清華大學醫(yī)學院生物醫(yī)學工程專業(yè),博士
1999-09至2003-07,清華大學熱能工程系熱能與動力工程專業(yè),學士
工作經(jīng)歷
2012-04至今,中國科學院理化技術研究所,歷任助理研究員、副研究員、研究員
2015-09至2016-12,美國哈佛大學醫(yī)學院及其附屬麻省總醫(yī)院,訪問學者
2010-06至2010-12,日本東北大學原子分子材料科學高等研究機構,研究助理
2009-06至2012-04,中國科學院半導體研究所,博士后
長期從事液態(tài)金屬材料和微流控技術的生物醫(yī)學應用研究:
1.?液態(tài)金屬材料的生物醫(yī)學應用,包括液態(tài)金屬神經(jīng)連接與修復技術,柔性電子與電子皮膚等;
2.?微流控芯片與器官芯片技術,通過模擬體內環(huán)境構建仿生平臺,研究環(huán)境、細胞、藥物之間的相互作用;
3.?微流體技術與液態(tài)金屬材料、微納加工技術、組織工程學等的跨學科研究。
1.?國家重點實驗室項目,液態(tài)金屬冷凍凝膠導管修復外周神經(jīng)損傷的研究;
2.?國家級項目,多通道液態(tài)金屬柔性神經(jīng)電極研發(fā);
3.?國家重點實驗室項目,仿生納米針尖制造及其抗菌機理研究;
4.?國自然面上項目,多層液滴微流控芯片提高微生物可培養(yǎng)性的研究;
5.?國自然面上項目,量子點結合微流控芯片識別循環(huán)腫瘤細胞的光學檢測方法研究;
6.?中科院重點部署項目,微流控芯片技術檢測循環(huán)腫瘤細胞在肺癌中的應用研究;
7.?北京市教委,基于微流體技術的體外血管系統(tǒng)構建;
8.?所級項目,小口徑人工血管構建關鍵技術探索。
[1] 桂林,高猛,葉子,李雷,液態(tài)金屬微流體學,上海科學技術出版社,2021。
[2] Huan Hu and Lei Li,?Micro/nanofabrication of IVD/POCT Biosensors, Bentham Science Publishers, Frontiers in Nanobiotechnology Vol. 1, 2020.
目前,已發(fā)表期刊論文50余篇,以第一或通訊作者在Bioactive?Materials,Science Bulletin,Biosensors and Bioelectronics等國內外知名SCI期刊發(fā)表論文30余篇(影響因子大于10的論文5篇,中科院1區(qū)TOP期刊論文7篇)。
[1] Xiao Sun, Xiaohong Wang, Bingjie Wu, Qianhong Yang, Congxiao Zhu, Huimin Zhang, Qian Li, Hongru Zhou, Minghui Guo, Lin Gui*, Lei Li*. A biomimetic 3D magnetically responsive scaffold with tunable and stable compression for dynamic 3D cell culture. Science China-Materials, 2025, 68, 652.
[2] Xiao Sun, Zhenming Li, Chunwei Li , Huimin Zhang, Wei Liu, Mingyang Liu, Lei Li*, Lin Gui*. Hydrophilic hard-magnetic soft robots: a new approach for precise droplet manipulation.?Nanotechnology and Precision Engineering, 2025, 8, 043012. (Nature亮點報道)
[3] Congxiao Zhu, Zonglin Huang, Hongru Zhou, Xuefeng Han, Lei Li*, Ningbei Yin*. Purified adipose tissue-derived extracellular vesicles facilitate adipose organoid vascularization through coordinating adipogenesis and angiogenesis. Biofabrication, 2025, 17, 025014.
[4] Siyuan Zhou, Lei Li*, Jianhua Cao, Xiubin Yang, Dayong Wu*. Transition from Procoagulation to Antiplatelet Effect: Applicationand Mechanism of Aspirin-Modified Chitosan in Small-DiameterVascular Grafts. ACS?Applied?Bio?Materails, 2024, 8, 763.
[5] Xilong Zhang, Zhongshan Deng*, Huize Song, Minghui Guo and Lei Li*. Liquid Metal Electromagnetic Wave Shielding and Absorbing (EWSA) Film for Solving Electromagnetic Interference in Flexible Sensor Devices.?Science China-Materials, 2024, 67, 3976.
[6] Xilong Zhang, Chang Liu, Rongyu Tang, Weichen Feng, Jingru Gao, Bingjie Wu, Zhongshan Deng, Jing Liu*, Lei Li*. Liquid metal neuro-electrical interface, Soft Sci, 2024, 4, 23. (Invited review)
[7] Sicong Liu,?Lei Li*,?Chanyuan Jiang,?Qianyu Wang,?Zhongshan Deng*. Synergistic injection of the thermosensitive hydrogel and bismuth-based alloy bone cement for orthopaedic repair. Science China-Technological Sciences, 2024, 67, 2153.
[8] Qingyue Guo,Lei Li*, Guanyue Gao, Qi Zhao, Xia Huang, Hao Wang, Bingxin Liu, Jinfang Zhi*.?Nanodiamonds inhibit the proliferation and migration of endothelial cells in a tumor/endothelial cells co-culture microfluidic system. Carbon, 2024, 218, 118671.
[9] Siyuan Zhou, Lei Li*, Enzehua Xie, Meixi Li, Jianhua Cao, Xiubin Yang*, Dayong Wu*. Small-diameter PCL/PU Vascular Graft Modified with Heparin-aspirin Compound for Preventing the Occurrence of Acute Thrombosis. International Journal of Biological Macromolecules, 2023, 249, 126058.
[10] Xilong Zhang, Lei Li*, Zhongshan Deng*. Liquid Metal-Based Flexible Bioelectrodes for Management of In-Stent-Restenosis: Potential Application. Biosensors, 2023, 13(8), 795.?
2014?中國制冷學會技術發(fā)明獎一等獎
2013?中國科學院科技成果在北京轉化先進團隊特等獎
2005?國際生物醫(yī)學工程聯(lián)合會杰出中國學生獎(全中國共6名)
人才隊伍